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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AXIN1
All Species:
34.55
Human Site:
Y346
Identified Species:
69.09
UniProt:
O15169
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15169
NP_003493.1
862
95635
Y346
S
V
D
G
I
P
P
Y
R
I
R
K
Q
H
R
Chimpanzee
Pan troglodytes
XP_001152990
821
90810
Y346
S
V
D
G
I
P
P
Y
R
I
R
K
Q
H
R
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_852321
867
95820
Y346
S
V
D
G
I
P
P
Y
R
I
R
K
Q
H
R
Cat
Felis silvestris
Mouse
Mus musculus
O35625
863
96295
Y346
S
V
D
G
I
P
P
Y
R
I
R
K
Q
H
R
Rat
Rattus norvegicus
O70239
827
92266
Y346
S
V
D
G
I
P
P
Y
R
I
R
K
Q
H
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508740
844
93228
Y328
S
V
D
G
V
P
P
Y
R
V
G
S
K
K
Q
Chicken
Gallus gallus
O42400
841
94913
Y346
S
I
D
G
I
P
P
Y
R
L
R
K
Q
H
R
Frog
Xenopus laevis
Q9YGY0
842
94441
Y346
S
V
D
G
I
P
P
Y
R
L
R
K
H
Y
R
Zebra Danio
Brachydanio rerio
P57094
835
94310
Y349
S
V
D
G
V
P
P
Y
R
Y
R
K
P
H
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V407
745
81700
I319
A
R
A
P
D
Y
P
I
R
L
T
R
D
L
L
Honey Bee
Apis mellifera
XP_001120373
693
78297
L280
A
T
Q
Q
T
R
A
L
D
L
R
P
K
P
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781992
855
95982
F330
T
D
S
S
V
D
G
F
P
V
R
S
R
Q
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.6
N.A.
86.6
N.A.
87
84.2
N.A.
43.2
73
67.5
64
N.A.
21.8
27.2
N.A.
33
Protein Similarity:
100
95.1
N.A.
91.2
N.A.
91.1
88.1
N.A.
59.4
82.9
79.4
74.8
N.A.
38
42.4
N.A.
50.3
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
53.3
86.6
80
80
N.A.
13.3
6.6
N.A.
6.6
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
80
100
93.3
86.6
N.A.
33.3
26.6
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
9
0
0
0
9
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
75
0
9
9
0
0
9
0
0
0
9
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% E
% Phe:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
75
0
0
9
0
0
0
9
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
9
59
0
% H
% Ile:
0
9
0
0
59
0
0
9
0
42
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
67
17
9
0
% K
% Leu:
0
0
0
0
0
0
0
9
0
34
0
0
0
9
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
9
0
75
84
0
9
0
0
9
9
9
0
% P
% Gln:
0
0
9
9
0
0
0
0
0
0
0
0
50
9
17
% Q
% Arg:
0
9
0
0
0
9
0
0
84
0
84
9
9
0
67
% R
% Ser:
75
0
9
9
0
0
0
0
0
0
0
17
0
0
0
% S
% Thr:
9
9
0
0
9
0
0
0
0
0
9
0
0
0
0
% T
% Val:
0
67
0
0
25
0
0
0
0
17
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
0
75
0
9
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _